Answer: The main raw materials of hydroxypropyl methyl cellulose (HPMC) : refined cotton, chloromethane, propylene oxide, other raw materials and alkali tablets, acid, toluene, isopropyl alcohol and so on.
Concerning modified celluloses, methyl cellulose was negative in the bacterial reverse mutation assay, in the in vitro chromosomal aberration test in mammalian cells and in host-mediated assays with yeast and bacteria. In vivo methyl cellulose was also negative in a chromosome aberration assay in rat bone marrow and in the dominant lethal assay in male rats. Carboxymethyl cellulose was negative in the bacterial reverse mutation assay, in the in vitro chromosomal aberration test in mammalian cells, performed only without metabolic activation, and in host-mediated assays.
Hydroxypropyl methylcellulose, often abbreviated to HPMC or also called hypromellose, is a chemical compound widely used as an aid in pharmaceutical and food products. HPMC is a type of cellulose ether, a derivative of natural cellulose, which is extracted from plant sources such as wood pulp or cotton fibers. This compound is specifically valued for its ability to serve as a thickener, stabilizer, emulsifier and film former. It has many functions.